| Peyton Manning's Career Passing Stats Versus Each Team Reviews | ||||||||||
| Team | W | L | Att | Com | Pct | Yards | Yds/Att | Long | Td | Int | QB Rating |
| Arizona Cardinals | 2-0 | 32 | 21 | 65.6 | 336 | 10.5 | 72 | 4 | 1 | 127.0 |
| Atlanta Falcons | 3-2 | 161 | 113 | 70.1 | 1287 | 8.0 | 36 | 14 | 7 | 104.7 |
| Baltimore Ravens | 8-2 | 333 | 209 | 62.7 | 2647 | 7.9 | 67 | 18 | 8 | 95.5 |
| Buffalo Bills | 7-4 | 338 | 209 | 61.8 | 2345 | 6.9 | 50 | 13 | 10 | 83.0 |
| Carolina Panthers | 2-2 | 136 | 81 | 59.5 | 1094 | 8.0 | 59 | 5 | 3 | 88.2 |
| Chicago Bears | 2-2 | 154 | 122 | 79.2 | 1017 | 6.6 | 53T | 8 | 3 | 103.3 |
| Cincinnati Bengals | 8-0 | 270 | 181 | 67.0 | 2118 | 7.8 | 69 | 20 | 5 | 107.6 |
| Cleveland Browns | 6-0 | 208 | 139 | 66.8 | 1463 | 7.0 | 51 | 5 | 4 | 87.0 |
| Dallas Cowboys | 2-2 | 159 | 107 | 67.2 | 1183 | 7.4 | 54 | 7 | 7 | 85.4 |
| Denver Broncos | 6-2 | 250 | 155 | 62.0 | 1645 | 6.5 | 63 | 15 | 5 | 92.8 |
| Detroit Lions | 3-0 | 98 | 73 | 74.4 | 842 | 8.5 | 39 | 10 | 2 | 125.4 |
| Green Bay Packers | 1-2 | 126 | 74 | 58.7 | 916 | 7.3 | 36T | 8 | 3 | 92.5 |
| Houston Texans | 16-3 | 720 | 474 | 65.8 | 5452 | 7.6 | 80T | 44 | 9 | 103.6 |
| Jacksonville Jaguars | 14-5 | 619 | 444 | 71.7 | 5241 | 8.4 | 76T | 38 | 13 | 108.8 |
| Kansas City Chiefs | 8-1 | 319 | 202 | 63.3 | 2500 | 7.8 | 56 | 15 | 9 | 91.4 |
| Miami Dolphins | 5-7 | 403 | 244 | 60.5 | 2957 | 7.3 | 80T | 18 | 18 | 60.5 |
| Minnesota Vikings | 3-0 | 97 | 74 | 76.2 | 862 | 8.8 | 58 | 9 | 3 | 120.7 |
| New England Patriots | 7-11 | 677 | 427 | 63.0 | 5049 | 7.4 | 78T | 40 | 24 | 90.6 |
| New Orleans Saints | 4-2 | 187 | 125 | 66.8 | 1790 | 20.5 | 86T | 15 | 5 | 96.3 |
| New York Giants | 3-1 | 148 | 101 | 68.2 | 1133 | 7.6 | 57T | 9 | 4 | 99.8 |
| New York Jets | 7-4 | 394 | 247 | 62.6 | 2695 | 6.8 | 41 | 13 | 11 | 78.4 |
| Oakland Raiders | 5-2 | 258 | 169 | 65.5 | 1909 | 7.4 | 50T | 16 | 9 | 93.6 |
| Philadelphia Eagles | 3-1 | 121 | 79 | 65.2 | 1031 | 8.5 | 80T | 8 | 3 | 103.7 |
| Pittsburgh Steelers | 3-2 | 177 | 109 | 62.0 | 1332 | 7.5 | 80T | 9 | 4 | 92.3 |
| San Diego Chargers | 6-4 | 434 | 273 | 62.9 | 3108 | 7.1 | 55 | 21 | 20 | 81.2 |
| San Francisco 49ers | 2-2 | 160 | 103 | 64.3 | 1203 | 7.5 | 61T | 5 | 6 | 81.4 |
| Seattle Seahawks | 2-2 | 122 | 83 | 68.0 | 1085 | 8.8 | 53 | 4 | 2 | 99.9 |
| St. Louis Rams | 2-1 | 104 | 60 | 57.6 | 621 | 5.9 | 36 | 5 | 1 | 87.0 |
| Tampa Bay Buccaneers | 3-0 | 122 | 90 | 73.7 | 881 | 7.2 | 52 | 5 | 3 | 99.7 |
| Tennessee Titans | 13-5 | 578 | 399 | 69.0 | 4559 | 7.8 | 68T | 31 | 13 | 100.9 |
| Washington Redskins | 3-1 | 142 | 94 | 66.1 | 1161 | 8.1 | 57T | 10 | 3 | 105.9 |
| Peyton Manning's Career Rushing Stats Versus Each Team Reviews | ||||||||
| Team | W | L | Att | Yards | Avg. | Td | Sacked | Yards | Fumbles |
| Arizona Cardinals | 2-0 | 1 | -1 | -1.0 | 0 | 1 | -4 | 0 |
| Atlanta Falcons | 3-2 | 6 | 16 | 2.7 | 0 | 8 | 57 | 0 |
| Baltimore Ravens | 8-2 | 15 | 26 | 1.7 | 0 | 14 | 108 | 1 |
| Buffalo Bills | 7-4 | 26 | 79 | 3.0 | 2 | 9 | 66 | 0 |
| Carolina Panthers | 2-2 | 4 | 10 | 2.5 | 0 | 6 | 13 | 1 |
| Chicago Bears | 2-2 | 5 | 26 | 6.5 | 0 | 5 | 46 | 1 |
| Cincinnati Bengals | 8-0 | 13 | 19 | 1.4 | 1 | 5 | 17 | 0 |
| Cleveland Browns | 6-0 | 14 | 36 | 2.5 | 0 | 2 | 10 | 0 |
| Dallas Cowboys | 2-2 | 8 | 11 | 1.3 | 0 | 3 | 20 | 1 |
| Denver Broncos | 6-2 | 20 | 21 | 1.0 | 0 | 3 | 14 | 3 |
| Detroit Lions | 3-0 | 3 | 7 | 2.3 | 0 | 2 | 10 | 0 |
| Green Bay Packers | 1-2 | 4 | -9 | -2.3 | 0 | 4 | 27 | 0 |
| Houston Texans | 16-3 | 37 | 32 | 1.1 | 0 | 26 | 154 | 2 |
| Jacksonville Jaguars | 14-5 | 42 | 30 | 0.7 | 3 | 15 | 102 | 2 |
| Kansas City Chiefs | 8-1 | 18 | 5 | 0.2 | 1 | 12 | 91 | 3 |
| Miami Dolphins | 5-7 | 20 | 61 | 3.0 | 2 | 18 | 124.5 | 0 |
| Minnesota Vikings | 3-0 | 7 | 19 | 2.7 | 0 | 3 | 19 | 0 |
| New England Patriots | 7-11 | 26 | 83 | 3.1 | 3 | 25 | 161 | 5 |
| New Orleans Saints | 4-2 | 7 | 16 | 2.3 | 0 | 5 | 26 | 0 |
| New York Giants | 3-1 | 6 | -6 | -1.0 | 0 | 4 | 25 | 0 |
| New York Jets | 7-4 | 23 | 96 | 4.1 | 1 | 13 | 76 | 0 |
| Oakland Raiders | 5-2 | 14 | 46 | 3.3 | 0 | 11 | 75 | 0 |
| Philadelphia Eagles | 3-1 | 6 | 23 | 3.8 | 0 | 4 | 26 | 0 |
| Pittsburgh Steelers | 3-2 | 5 | 13 | 2.6 | 0 | 21 | 1 | |
| San Diego Chargers | 6-4 | 13 | 4 | 0.3 | 1 | 15 | 90 | 1 |
| San Francisco 49ers | 2-2 | 1 | 0 | 0.0 | 0 | 6 | 30 | 0 |
| Seattle Seahawks | 2-2 | 2 | -1 | -0.5 | 0 | 3 | 6 | 0 |
| St. Louis Rams | 2-1 | 4 | 6 | 1.5 | 1 | 4 | 21 | 0 |
| Tampa Bay Buccaneers | 3-0 | 4 | -7 | -1.7 | 0 | 1 | 5 | 0 |
| Tennessee Titans | 13-5 | 20 | 55 | 2.7 | 1 | 13 | 80 | 2 |
| Washington Redskins | 3-1 | 4 | -2.0 | -0.5 | 1 | 5 | 34 | 2 |
